It was built between 1818 and 1821 on a former monastery of the Augustinians, as a part of the new urban and architectural plan created by Giuseppe Valadier for Piazza del Popolo and its Tridente.

The building, which borders the church of Santa Maria in Montesanto, shows a characteristic long facade divided into three parts.

[1] In the mid-nineteenth century it was bought by the nobleman and art collector Giampietro Campana, who here preserved and exhibited a part of his famous collection of Greek and Roman sculpture and antiquities.

The building was raised in 1872, during the restoration works that involved the whole Rione after the proclamation of Rome as the Capital of Italy.

Today part of the building houses the Piranesi Hotel, while the rest is used for private homes.