Via del Babuino is a street in the historic centre of Rome (Italy), located in the rione Campo Marzio.
In 1525, works commissioned by Pope Clement VII gave the street a new aspect and a new name: Via Clementina, in honor of its creator.
In this occasion a statue of Silenus, an ancient classical deity related to springs and fountains, was also placed on the street.
The statues was compared to a monkey, and was thus nicknamed Babuino (Romanesco for "Baboon"); this name soon came to indicate the whole street.
A plate remembers the twinning ratified on October 16, 2002 between Via del Babuino and Madison Avenue in New York City.