It was moved to premises adjacent to the former Benedictine Monastery of San Nicolò l'Arena, and changed its name to "Vittorio Emanuele II Hospital".
The palace also housed two prominent Cafe and drink establishments during the early to mid 20th-century: La Birraria Svizzera and the Gran Caffè Lorenti.
After the transfer of the hospital, Palazzo Tezzano remained the seat of the Court until 1953, when the new headquarters building in Giovanni Verga Square completed and inaugurated.
The three-story, late-Baroque-style palace is notable for the contrast between the white stone windows with balustrades and monumental pilasters, and in between plain dark volcanic basalt plaster.
The palace overlooks the ruins of the Ancient Roman amphitheater and a block from the church of San Biagio at the western end of the piazza.