Presently the palace houses the faculty of Foreign Languages and Literature of the University of Bologna.
The interiors were decorated with frescoes depicting classic mythology by Orazio Samacchini, allegories of the feats of Lorenzo Sabbatini, and a series of the Life of Cyrus by Pellegrino Tibaldi, and the about the Charity of Alexander the Great by Tommaso Laureti.
In the library were kept numerous instruments and maps that served the meetings of the literary and scientific society, the Accademia degli Oziosi, which was founded by Pompeo.
In 1691, bereft of Vizzani heirs, the palace became property of Senator Francesco Ratta, and in 1726 of marchesa Elisabetta Bentivoglio, and in 1732, of Cardinal Lambertini, the future Pope Benedict XIV.
The Lambertini family expanded the palace, utilizing Carlo Lodi and Felice Giani, to paint further frescoes.