The Palazzo dei Priori is a medieval-Renaissance palace in center of the town of Fermo, region of Marche, Italy.
It underwent reconstructions, lastly in 1525, when the dual staircase in the facade was built leading to a portal atop which stand a large bronze statue of a seated Pope Sixtus V in the act of benediction.
Among the artists featured are Andrea da Bologna, Francescuccio di Cecco Ghissi, Jacobello del Fiore (Life of Santa Lucia), Vittore Crivelli ( Crucifixion), Vincenzo Pagani, Giuliano Presutti, Giovanni Lanfranco (Pentecost), and Peter Paul Rubens (Adoration of the Shepherds, 1608).
The palace has a Sala del Mappamondo (Hall of the World Map), completed in 1688 by Adamo Sacripante on commission of the local Cardinal Decio Azzolino.
It is now part of the larger collection of the Biblioteca Spezioli, housed in this palace and the adjacent building.