[2] As a result, the Palo Alto Medical Clinic was founded in 1930 by Russell V. Lee, and five other doctors.

[4] The early doctors and founding partners to form the clinic included Edward "Fritz" Roth, Blake Colburn Wilbur, Herbert Niebel, Milton Saier, and Esther Bridgman Clark.

[7] The building is in a U-shape, and built of concrete, stucco and features clay roof tiles and a second floor rustic wood balcony.

[8][9] Arnautoff's mural series all were medically-themed murals done in the recessed under a loggia with four panels of modern medicine and other panels showing primitive medicine, and additionally he four painted medallions of Joseph Lister, Hippocrates, Louis Pasteur, and Wilhelm Röntgen are on the exterior wall of the loggia.

[9][10] The four murals done in color feature modern medicine and depict Luther Emmett Holt, William Osler, and Harvey Cushing.