Pampachiri is a rural district in Andahuaylas Province in the Apurímac Region of southern Peru.

Before the Spanish conquest, it was populated by the Inca, Chanka and Wari peoples who have left numerous archeological sites in the area.

High in the puna area is Panqulla, a spectacular stone forest which is an unusual geological phenomenon of volcanic rocks in the shape of large smooth cones.

The main economic activities of the population are subsistence agriculture and cattle raising (lowlands) and alpaca and vicuña husbandry (highlands).

Typical crops grown in Pampachiri include potatoes, corn, alfalfa, and tuna, the fruit of the cactus indigenous to the region.