Panaeolus cambodginiensis is a potent hallucinogenic mushroom that contains psilocybin and psilocin.

The stem is 5 to 10 centimetres (2.0 to 3.9 in) tall, 4 mm thick, and slightly swollen at the base.

The spores are black, shaped like lemons, smooth, measuring 11 x 8 μm.

Panaeolus cambodginiensis is mushroom that grows on dung of water buffalo.

Merlin and Allen (1993) reported the presence of psilocybin and psilocin, up to .55% and .6%, respectively.