Panaqolus claustellifer is a species of catfish in the family Loricariidae.

It is native to South America, where it occurs in the Takutu River and the Branco River in Brazil and Guyana.

[1] The species reaches 6.2 cm (2.4 inches) SL.

In the aquarium trade, it is typically referred to either as the blood-red tiger pleco or by one of its two associated L-numbers, which are L-306 and LDA-064.

[2] Its specific epithet means "keyhole-bearing" in Latin, referring to the distinctive markings present on the species' snout.