Pancreatic mucinous cystic neoplasm

[2] Histologic evaluation of MCNs shows mucin-producing columnar epithelial lining, which is surrounded by ovarian-like stroma.

Factors that predict malignancy include loculated appearance, mural nodules, papillary projections, p53 immunoreactivity, and loss of ovarian-like stroma.

In individuals who are eligible to undergo surgery, who are found to have asymptomatic cysts that appear to be benign MCNs or IPMNs, then surveillance imaging may be considered.

[1] In individuals unable to undergo surgery, there may be a role for endoscopic ultrasound (EUS) guided ablation with alcohol lavage with paclitaxel injection.

[7] A study in 2012 found that amongst individuals undergoing surgical resection of a pancreatic cyst, about 23 percent were mucinous cystic neoplasms.

Relative incidences of various pancreatic neoplasms, with mucinous cystic neoplasm annotated near bottom right. [ 6 ]