express the variation of the extensive volume of a mixture in respect to composition of the masses.
It is the partial derivative of volume with respect to the mass of the component of interest.
defined as: The PSV is usually measured in milliLiters (mL) per gram (g), proteins > 30 kDa can be assumed to have a partial specific volume of 0.708 mL/g.
[1] Experimental determination is possible by measuring the natural frequency of a U-shaped tube filled successively with air, buffer and protein solution.
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