[2] In 1841, Dr Farquhar McCrae, a wealthy surgeon, purchased land called 'La Rose' in what is now known as Pascoe Vale South.

[2] Significant development of Pascoe Vale South took place after the tramline was extended to Bell Street in 1927, with the post office opening on 1 August 1927.

In Pascoe Vale South, Christianity was the largest religious group reported overall (56.2%) (this figure excludes not stated responses).

Eight bus routes service Pascoe Vale South: For cyclists, the suburb adjoins the Moonee Ponds Creek Trail to the west.

Tram route 58 provides public transport through the suburb, from the Bell Street terminus and along Melville Road, to the city.