A member of The Groundlings comedy troupe, as an actress she is best known for her role as Madisynn King on She-Hulk: Attorney at Law.
[1] She has had guest-starring roles on Reno 911!, Mr. Mayor, Superstore, The Middle, Modern Family, and Splitting Up Together.
Guggenheim also wrote for and acted in Barely Famous and additionally, voiced Patty Mime on SuperMansion.
[7] Florida Girls and She-Hulk: Attorney at Law director Kat Coiro commented that Guggenheim and Wong’s riffing on subjects such as The Sopranos and cocktails was improvised and un-scripted, with Coiro quoted as saying "That came purely from the actors' comedic chemistry and us going, 'We've got to throw some cameras on these two because they're so funny."
[9] Guggenheim told the media she lives in the old apartment of fellow MCU actor Chris Hemsworth in Los Angeles and still occasionally receives his mail at the address.