Pavel Kysilka (born 5 September 1958 in Boskovice) is a Czech economist, who was head of the Central Bank of the Czech National Bank from 1997 to 1998.

From September 1990 to the end of 1991, he was an advisor to the Minister for Economic Politics and Local Affairs.

On 17 December 1997, head of the Central Bank, Josef Tošovský became Prime Minister in the Czech Republic's caretaker government which was formed by President Václav Havel, in the aftermath of Vaclav Klaus' minority government collapse in November 1997.

On 22 June 1998, after the 1998 election, Tošovský went back to his role as head of the Central Bank, and Kysilka returned to being vice-head of the Central Bank.

He continued in this role until 10 February 1999, and finished at the Central Bank on 30 September 1999.