In 1913, he began to study violin with José Lorenzo Llamozas, and soon entered the Superior School of Music, where his teachers included Juan Bautista Plaza.

Ríos Reyna organized for ten years the Sunday concerts at the National Library.

In 1968, created the Chorale of the Caracas Philharmonic, and the Central University of Venezuela Student Orchestra.

Pedro Antonio Ríos Reyna died in an automobile accident, New York City, February 13, 1971.

In 1983, in honor for his work and legacy the principal concert hall of Venezuela's most important arts center, the Teresa Carreño Cultural Complex was named after him.