[2] As a child, he began playing American football alongside his three brothers after his father Gabriel became a coach of the sport.

[3] Seeing the potential for his children to make it to the National Football League (NFL), Gabriel moved his family to St. George, Utah in 2012.

[6][7][8] Sewell became an immediate starter during his freshman year for the Ducks in 2018, starting seven games but missing six due to a high ankle sprain.

[11][12] In addition, he and former Alabama quarterback Tua Tagovailoa were selected as co-recipients of the 2019 Polynesian College Football Player of the Year award.

[20] In Week 14 of the 2022 season, Sewell had a nine-yard reception late in the fourth quarter to give the Lions a crucial first down in the 34–23 victory over the Minnesota Vikings.