He played college football at Ohio State, where he was a unanimous All-American in 2019 before being selected by the Detroit Lions third overall in the 2020 NFL draft.

[18] The following week, he recorded his first career interception off a pass thrown by Arizona Cardinals quarterback Kyler Murray.

[19] Okudah was placed on injured reserve after he underwent surgery to resolve a core muscle injury on December 15.

[20][21] During the Lions' 2021 season opener against the San Francisco 49ers, Okudah ruptured his Achilles tendon and was placed on injured reserve.

[22] Okudah was traded to the Atlanta Falcons on April 13, 2023, in exchange for a fifth-round pick in the 2023 NFL draft.