Designed to provide professional training to employees, the Allentown Branch School offered evening courses in engineering.

Along with the new facilities came a new mission to provide the first two-year Penn State baccalaureate degrees and expanded continuing education programs.

In 2003, Penn State Lehigh Valley opened a second site, the Corporate Learning Center, located at 100 Brodhead Road in Bethlehem.

Penn State shared the facility with Lehigh Valley College until that school closed in December 2009.

Penn State–Lehigh Valley teams participate in the United States Collegiate Athletic Association (USCAA).