Here, the route runs through small areas of agriculture before heading away from the creek and the railroad line and continuing into forests and passing to the west of Sizerville State Park.

In the community of Keating Summit, the route intersects the northern terminus of PA 607 and heads north-northwest through more forests with some fields, turning to the northwest.

The route turns to the northwest and heads into more agricultural areas with some homes, with the Portage Creek and the railroad line a short distance to the west of the road.

The two routes pass through more residential areas before US 6 splits from PA 155 by heading west on Grand Army of the Republic Highway.

The road runs through Sartwell and enters Eldred Township, continuing northwest through wooded areas with some fields and homes, ending at PA 446.