The route runs through suburban areas to the northeast of Scranton, serving Dunmore, Throop, Olyphant, and Blakely.

By 1930, the route was realigned to run from US 6 (Main Street) in Dickson City northwest to PA 407 in Wallsville.

The road heads past a few businesses before running through residential areas, widening into a four-lane divided highway as it comes to a partial cloverleaf interchange with I-81/US 6.

Past this, the route becomes Oneill Highway, a five-lane road with a center left-turn lane, and runs through commercial areas, passing to the east of the Penn State Worthington Scranton campus.

PA 347 heads into the borough of Olyphant and it passes more residences before crossing a Delaware-Lackawanna Railroad line and turning northwest onto West Lackawanna Avenue.

The route heads through residential areas, turning west to fully enter Dickson City.

The road heads north through a mix of farmland and woodland with some homes, running through the community of Millars School.

The route intersects PA 632 and continues north through more rural areas a short distance to the east of I-81.

[12][13] In the 1960s, PA 347 was realigned and extended south along its present alignment to US 11/PA 307 at the intersection of Blakely and Green Ridge streets in Dunmore.

[15] The southern terminus of PA 347 was cut back to SR 2020 at the intersection of Drinker and Blakely streets by 1990.