PA 845 begins at an intersection with US 62 in Sandy Lake Township, heading west on two-lane undivided Walnut Street.

The road runs through wooded areas with some homes, heading into the borough of Stoneboro.

PA 845 curves northwest onto Linden Road, entering forested areas.

The route turns north as it passes to the west of Sandy Lake.

PA 845 heads into Lake Township and becomes Stoneboro Lateral Road, running through a mix of farmland and woodland with a few residences.