The northern terminus is at the New York-Pennsylvania border in Oakland Township, where the road continues northward as New York State Route 79 (NY 79).

PA 92 begins at an intersection with US 11 in the borough of West Pittston in Luzerne County, heading northwest on two-lane undivided Exeter Avenue.

The road heads through residential areas, crossing a Luzerne and Susquehanna Railway line before continuing past more homes with some businesses.

PA 92 curves northwest and continues into forested areas to the southwest of the river, crossing into Exeter Township and becoming Sullivan Trail.

The road heads north past homes in the community of Harding, running through farmland with some development before continuing northeast into more forests.

[1][2] PA 92 enters Exeter Township in Wyoming County and becomes an unnamed road, heading northwest through forests to the southwest of the North Branch Susquehanna River.

The route turns northwest and resumes alongside the Reading Blue Mountain and Northern Railroad line and the North Branch Susquehanna River, heading through a mix of farmland and woodland with some residences and passing through McKune.

The route heads into dense forests with occasional residences and curves to the east, turning north again and crossing into Lemon Township.

PA 92 winds east through more woodland with some fields to the north of the creek, heading into the borough of Nicholson and becoming State Street.

Past this, PA 92 turns northeast into a commercial area and crosses Nine Partners Creek, coming to an interchange with access to and from the northbound direction of I-81.

[citation needed] Another bridge over a tributary of the Susquehanna River has been weight restricted for loads over 20 tons,[6] but as of 2018 a truck route has not been signed.