Pentafluorobenzene is an organofluoride compound with the molecular formula C6HF5.

[1] The compound consists of a benzene ring substituted with five fluorine atoms.

[2] The substance is a colorless liquid with a boiling point similar to that of benzene.

[3][4] It is prepared by defluorination of highly fluorinated cyclohexanes over hot nickel or iron.

[5] Another method involved dehydrofluorination of polyfluorinated cyclohexane using hot aqueous solution of KOH.