The station was on the Great Western Railway's Newport - Pontypool - Blaenavon - Brynmawr Eastern Valley "Upper Level" line.

The line opened to passengers in 1879 but the station at Pentrepiod was not added until 13 July 1912.

As passenger services along the entire route were withdrawn on 5 May 1941[1][2] (ostensibly due to wartime economies, but they never resumed after hostilities ended), the station had an active life of less than 30 years.

The line never generated much passenger traffic as it only served a number of small catchments and had only been opened (originally by the LNWR) as a competitor to the Great Western Railway "Lower Line" which ran from Newport - Blaenavon along the valley floor, the two services sharing the same track from leaving the main line at Llantarnam until they diverged at Trevethin Junction just north of Pontypool Crane Street station.

The lower line track was lifted from Blaenavon to Trevethin Junction shortly afterward.