Perfluoromethylcyclohexane is a fluorocarbon liquid—a perfluorinated derivative of the hydrocarbon methylcyclohexane.

Perfluoromethylcyclohexane can be manufactured by the Fowler process, which involves moderating the action of elemental fluorine with cobalt fluoride in the gas phase from toluene.

This is preferred as the starting material over methylcyclohexane as less fluorine is required.

[1] Perfluoromethylcyclohexane is chemically inert and thermally stable (to over 400 °C).

[3] In common with other cyclic perfluorocarbons, perfluoromethylcyclohexane can be detected at extremely low concentrations, making it ideal as a tracer.