The periventricular nucleus is a thin sheet of small neurons located in the wall of the third ventricle, a composite structure of the hypothalamus.
The intermediate portion aids in production of thyroid releasing hormone, somatostatin, leptin, gastrin, and neuropeptide Y.
Lastly the caudal region aids in sympathetic nervous system regulation, and is regarded as the rage center.
One way is its expression of neuropeptide Y, which has an impact on the hypothalamic pathway responsible for GnRH secretion.
[3] The periventricular nucleus has also been shown to have many neurons that express kisspeptin, which generates a surge in LH, which ultimately leads to the release of GnRH.