Trillium persistens, the persistent trillium, is a North American species of flowering plants in the genus Trillium of family Melanthiaceae (formerly Trilliaceae).

The plant is also called the persistent wakerobin.

[2][3] Persistent trillium is an endangered herbaceous perennial plant that grows to a height of 20–30 cm, with three leaves in a whorl near the top of the stem just below the flower; each leaf is broad lanceolate, 3–9 cm long and 1.5–3.5 cm broad.

The white flower has three petals, each petal 2–3.5 cm long and 0.5–1 cm broad.

[4] This plant has a limited range in parts of the United States in the northeastern Georgia and northwestern South Carolina.