[2] Werner de-committed from Notre Dame during the season and re-opened his recruitment before opting to attend Ohio State.

[16] During the beginning of training camp, Werner competed against second-year veteran Zack Baun to be the starting weakside linebacker.

[17] Head coach Sean Payton named Werner the primary backup weakside linebacker, after the Saints signed Kwon Alexander to become the starter.

[18] On September 9, 2021, Werner made his professional regular season debut, appearing on special teams before exiting the Saints' 38-3 home-opening victory over the Green Bay Packers.

On January 1, 2022, Werner received a fine of $5,472 from the NFL due to a Horse-collar tackle on Miami Dolphins' running back Duke Johnson.