Pettisville is an unincorporated community and census-designated place (CDP) in Clinton and German townships, Fulton County, Ohio, United States.

Pettisville was laid out in 1857, and most likely was named for one Mr. Pettis, a railroad contractor.

Via County Road 19 it is 0.8 miles (1.3 km) north to Ohio State Route 2, which leads east 5 miles (8 km) to Wauseon, the Fulton County seat.

Archbold is 5 miles (8 km) west of Pettisville via County Road D. According to the U.S. Census Bureau, the Pettisville CDP has an area of 0.97 square miles (2.5 km2), all of it land.

This Fulton County, Ohio state location article is a stub.