6 species (see text) Phrynomedusa is a genus of tree frogs from the Southeast and South regions in Brazil.

[2] Phrynomedusa occur in mountain streams and associated ponds in the Atlantic Forest.

Only two species are known with certainty to occur in protected areas.

The iris is bicolored (a horizontal diffuse dark stripe in middle of eye separating dark yellow in upper and lower surfaces).

They lack the flash colors on flanks, preaxial, and postaxial margins of thighs present in the related phyllomedusid genera.