A few of the methods for determining individual relationships between the DNA sequence and physiological function include metabolic pathway engineering[1] and RNAi analysis.
[2] The relationships derived from methods such as these are organized and processed computationally to form distinct networks.
The key elements of the NSR Project are the databasing of physiological, pharmacological, and pathological information on humans and other organisms and integration through computational modeling.
[9][10][11][12] Collaborative physiomics research is promoted in part by the open availability of bioinformatics software such as simulation programs and modelling environments.
Examples of openly available software include: Tools such as these are developed using markup languages specific to bioinformatics research.