Phytochelatin

They are found in plants, fungi, nematodes and all groups of algae including cyanobacteria.

Phytochelatins act as chelators, and are important for heavy metal detoxification.

A mutant Arabidopsis thaliana lacking phytochelatin synthase is very sensitive to cadmium, but it grows just as well as the wild-type plant at normal concentrations of zinc and copper, two essential metal ions, indicating that phytochelatin is only involved in resistance to metal poisoning.

[4] Because phytochelatin synthase uses glutathione with a blocked thiol group in the synthesis of phytochelatin, the presence of heavy metal ions that bind to glutathione causes the enzyme to work faster.

[6] Phytochelatin seems to be transported into the vacuole of plants, so that the metal ions it carries are stored safely away from the proteins of the cytosol.

Chemical structure of phytochelatin. n = 2–11.