The amplified number of proliferated cells makes it easier to test different lymphocyte functions, biological mechanisms, and response to different stimuli.
[2] Pokeweed mitogen is also used in research studies to stimulate different lymphocytes and observe change.
When looking at deficiency of CD26 in knockout mice, after stimulation with PWM the role of CD26 in development of CD4+ T cells was observed.
[3] Another study where PWM was used as a stimulus was in the proteome analysis of lymphocytes of different immune phenotypes in cows.
[6] Other studies in mice showed that PWM contributes to weight-loss effects and increased glucose uptake which makes this lectin a subject for implementation in diabetes or obesity in humans.