SIGLEC10

89790243958ENSG00000142512ENSMUSG00000030468Q96LC7Q80ZE3NM_001171161NM_033130NM_001322105NM_172900NM_001382486NP_001309034NP_149121NP_766488NP_001369415Sialic acid-binding Ig-like lectin 10 is a protein that in humans is encoded by the SIGLEC10 gene.

[5][6] Siglec-G is often referred to as the murine paralog of human Siglec-10 [7] Like most but not all other Siglecs, Siglec-10 bears an ITIM (Immunoreceptor tyrosine-based inhibitory motif) within its cytoplasmic domain.

[8] It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).

Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs.

[supplied by OMIM][6] This article on a gene on human chromosome 19 is a stub.