Alongside detachments from the Einsatzgruppen of the SD and the 1st SS Infantry Brigade of the Waffen-SS, it perpetrated mass murder in the Holocaust and was responsible for large-scale crimes against humanity targeting civilian populations.

[2] The goals of the police battalions were to secure the rear by eliminating the remnants of the enemy forces, guarding the prisoners of war, and protecting the lines of communications and captured industrial facilities.

[5] When the regiment crossed the German-Soviet border, it came under the control of Friedrich Jeckeln, the Higher SS and Police Leader (HSS-PF) for Army Group South in Ukraine.

During the summer months, the battalion took part in joint actions with the 1st SS Infantry Brigade of the Waffen-SS, both providing support and undertaking independent killings.

[7] The killing activities of both the Einsatzgruppen detachments and the Police Regiment South slowed down the farther the Wehrmacht advanced, as more Jews were able to escape east and the density of the pre-war Jewish population was lower in Eastern Ukraine.