[1] Polybia paulista are found in tropical areas of Argentina, Paraguay and are prevalent in Brazil, specifically São Paulo.
This time can fluctuate depending on the season, warmer temperatures allow faster work rate of wasps causing quicker construction of the nest.
[6] The diverse organization of social structure creates different partitioning locations, collecting and transporting or storing resources.
[6] Plant fibre or pulp is also foraged, and typically is collected through the months of August to September and December to January.
[6] Finally carbohydrates are forged year round for energy and is important in the diets of adult wasps.
Wasps seem to feed primarily on cactus fruits, and focus on the cacti species which are in abundance and easily available during that time of year.
[6] The development of envelopes helps regulate a common concern with the loss of water in eggs, which causes the embyrosgenesis to become dormant.
[6] Polybia paulista have 5 larval instars and allows the growth and development of multiple morphological features.
[10] Head size typically increases with instars but amount of growth is dependent on biotic an abiotic influences.
The toxins are produced by peptides that have multiple actions, such as pain oedema formation, hemolysis, chemotaxis of PMLs and most cell degranulation.
[11] The variety of peptide composition for venom in intra and inter nest individuals, creates different potencies and toxicity.
[5] The low molecular weight compounds of wasps venom cause anticonvulsant and anxiolytic effects on bioassays; which could be a used to help treat epilepsy.
[13] Research has also shown that the venom of P. paulista contains an antimicrobial agent, Mastoparan, that inhibits all developmental forms of Trypanosoma cruzi, the parasite that is responsible for Chagas disease.