It has been represented in the House of Commons of the UK Parliament since 2019 by Apsana Begum, who was elected as a Labour Party MP.

[n 2] The whip was withdrawn on 23 July 2024, as a result of her voting to scrap the two child benefit cap, and she was suspended from the Parliamentary Labour Party.

Parliament accepted the Boundary Commission's Fifth Periodic Review of Westminster constituencies which proposed the seat's creation for the 2010 general election, since when it has consisted of the following electoral wards: Alternative names, including "Tower Hamlets South" and "Poplar and Millwall" were rejected following public consultation.

Now the area around Canary Wharf is one of the country's largest financial districts and has several landmark skyscrapers, such as One Canada Square.

At the end of 2012, 6% of the population of the constituency were unemployment benefit claimants, ranking sixth among London seats (the highest percentage was Tottenham at 7.9%), and above the London-wide average of 3.9%.