During the restoration by emperor Honorius in the early 5th century, the arch was strengthened in opus mixtum, and over it three large windows were opened.

In 537, the area between Porta Salaria and Castro Pretorio was the location of the siege by the Goth king Witigis against the troops of Belisarius.

The gate was damaged by the artillery fire of the Italian troops, and the following year it was demolished.

The 1921 demolition uncovered several funerary monuments of the sepulchres that flanked the old Via Salaria and that had been re-used to erect the towers.

A copy of the sepulchre of Quintus Sulpicius Maximus, an 11-year-old boy, is now visible in Piazza Fiume (the original is the Musei Capitolini).