Portland Christian School, based in Louisville, Kentucky, United States, is a private Christian school traditionally supported and affiliated with those Churches of Christ which held to a premillennial eschatology characteristic of Robert Henry Boll.

Founded in 1924 in the rear of the Portland Avenue Church of Christ in the Portland neighborhood with Boll's support, today the school system has over four hundred students at its campus on the east side of Louisville.

The former college-level division of PCS was the School of Biblical Studies, which became Kentuckiana Bible College.

[1] Portland Christian School was started with a missionary emphasis and was operated as a tuition-free institution until 1986.

The PCS Eagles won the 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, and 2005 KHSAA District 21 Baseball Championship.