Portneuf-sur-Mer (French pronunciation: [pɔʁnœf syʁ mɛʁ]) is a municipality in the Côte-Nord region of the province of Quebec in Canada.

In 1788, a chapel was built at the mouth of the Portneuf River and dedicated to Saint Anne.

[1] Permanent settlement began in around 1845, and the community had several names over time: Saint-Georges in 1848 (after the surveyor Georges Duberger), Portneuf Mills in 1882 (due to the presence of a mill), and Hamilton Cove in 1883 (named after a forestry company).

In 1902, the place was incorporated as the United Township Municipality of Sainte-Anne de Portneuf, when it split off from the Township of Saint-Paul de Mille-Vaches (now part of Longue-Rive).

[1] On January 1, 1950, it lost part of its territory when the Municipality of Saint-Luc-de-Laval was created (which was annexed into Forestville in 1980).