Potamolepidae is a family of freshwater sponges, with seven genera:[1] This family contains freshwater sponges with a variety of body shapes, ranging from encrusting, massive to arborescent with irregular lobes, ridges or branches.

Gemmules are located at the sponge base or strictly adhering to the substrate.

[2] When present, the ectosomal skeleton has microscleres in the dermal membrane.

It is loose and irregular at the sponge base and notably dense at the surface and more.

[2] Tropical areas off Africa, South America and around New Caledonia and Fiji.