[1] The compound is prepared by the reaction of titanium dioxide with a mixture of KH2PO4 and K2HPO4 near 1300 K. The potassium salts serve both as reagents and flux.

The high degree of birefringent walk-off between the pump signal and idler beams present in this material limit its use as an optical parametric oscillator for very low power applications.

However, it is prone to photochromic damage (called grey tracking) during high-power 1064 nm second-harmonic generation which tends to limit its use to low- and mid-power systems.

Periodically poled potassium titanyl phosphate (PPKTP) consists of KTP with switched domain regions within the crystal for various nonlinear optic applications and frequency conversion.

The interactions in PPKTP are based upon quasi-phase-matching, achieved by periodic poling of the crystal, whereby a structure of regularly spaced ferroelectric domains with alternating orientations are created in the material.