Powell High School is a high school in Powell, in the northwest part of the U.S. state of Wyoming.

The district is bordered by Montana on the north and Yellowstone Park on the west.

The school is in the 3A classification for Wyoming sports.

In the fall of 2008, after a $20 million reconstruction project, mice invaded the high school building and infested its classrooms.

This Wyoming school-related article is a stub.