Precious Blood Church of Holyoke, Massachusetts, burned on May 27, 1875, killing 78 people.

It is one of the deadliest fires in American history, and was also known by newspapers domestic and foreign as "The Holyoke Disaster".

Panic caused people to rush from the upper levels to a front door.

The event and its aftermath were also later depicted in some detail in the Franco-American novel Mirbah by Emma Port-Joli Dumas, originally published in Holyoke's La Justice.

[3] The church complex is located on the city block formed by Cabot, South East, Clemente,[a] and Hamilton Streets.