It was completed and opened for use on July 14, 1943, the birthday of Field Marshal Plaek Phibunsongkhram, Prime Minister at that time, with Rear Admiral Luang Thamrongnawasawat (Thawan Thamrongnawasawat) the Minister of Justice presided over the opening ceremony.

The bridge was named in honour of Pridi Banomyong and Luang Thamrongnawasawat, who were key figures in the government who were born in Ayutthaya.

The foot of the bridge on the outer Ayutthaya Island lies near Wat Phichai, a place where Phraya Tak (later King Taksin) used as a breakout point for the Burmese army to the east before the fall of Ayutthaya in 1767.

It was the idea of Pridi Banomyong who wants the Ayutthaya people to come back to live in the city.

However, the Pridi-Thamrong Bridge is still in operation, being converted into a thoroughfare for compact cars and motorbikes.