1570 – 12 March 1605), of the Bagrationi dynasty, was a crown prince (batonishvili) of Kakheti, a kingdom in eastern Georgia.
George revolted against David, who managed to pacify his defiant brother through awarding him a large estate.
George was cast in prison and released when his father, Alexander II, was able to resume his reign upon David's death.
He functioned as a regent during his father's absence at the Safavid Iranian court from early 1604 to March 1605.
In August 1604, he received Russian ambassadors and in October employed their armed entourage of 40 musketeers in defeating the expedition of the governors of Ganja and Shemakha against the frontier town of Zagem.