Homeward bound, she was at Saugor on 17 December, reached the Cape on 17 February 1817 and St Helena on 8 March, and arrived at the Downs on 6 May.

[2] EIC voyage #4 (1818–1819): Captain Harris sailed from Portsmouth on 31 March 1818, bound for Madras and Bengal.

[2] EIC voyage #5 (1820–1821): On 28 February 1828 Prince Regent, Captain John Innes, grounded on the South Shore, at Gravesend, Kent, near Pitcher's Dock; she was on her way to Madras and Bengal, and it was expected that she would be got off on the next tide.

Homeward bound, she crossed the Second Bar on 14 January 1821, reached the Cape on 24 March and St Helena on 15 April, and arrived at the Downs on 10 June.

Homeward bound, she was at Saugor on 27 December, reached the Cape on 27 February 1823 and St Helena on 14 March, and arrived at the Downs on 11 May.

Homeward bound, she was at Saugor on 9 January 1825, reached St Helena of 30 April, and arrived at the Downs on 7 June.

Homeward bound, she was at Saugor on 16 January 1829, reached St Helena on 28 April, and arrived at the Downs on 17 June.

[8] EIC voyage #10 (1833–1834): Captain Richard Aplin sailed from the Downs on 14 April 1833, bound for China.Price Regent reached Penang on 31 August and arrived at Whampoa on 26 September.

Homeward bound, she crossed the Second Bar on 17 January 1834, reached St Helena on 29 March, and arrived back in the Downs on 17 May.