He carves himself a niche as a soldier in search and rescue missions alongside Shadowcat's father, Carmen Pryde,[17] and witnesses Cain's transformation into Juggernaut when he touches a ruby with an inscription on it in an underground temple.
In Cairo, he meets a young girl named Ororo Munroe (later known as Storm), who is a pickpocket, and the Shadow King, a powerful mutant who is posing as Egyptian crime lord Amahl Farouk.
There, he meets a man going by the name of Magnus (who would later become Magneto), a Holocaust survivor who works as a volunteer in the clinic, and Gabrielle Haller, a woman driven into a catatonic coma by the trauma she experienced.
The two friends reveal their powers to each other when they fight Nazi Baron Wolfgang von Strucker and his Hydra agents, who kidnap Gabrielle because she knows the location of their secret cache of gold.
[14] Xavier discusses his candidates for recruitment to his personal strike force, the X-Men, with Moira, including those he passes over, which are Kurt Wagner, Piotr Rasputin, Pietro and Wanda Maximoff, and Ororo Munroe.
In addition, he seeks to foster mutant-human relations by providing his superhero team, the X-Men, as an example of mutants acting in good faith, as he told FBI agent Fred Duncan.
[29] With his inherited fortune, he uses his ancestral mansion at 1407 Graymalkin Lane in Salem Center, Westchester County, New York as a base of operations with technologically advanced facilities, including the Danger Room – later, Fantomex mentions that Xavier is a billionaire with a net worth of $3.5 billion.
[37] When the X-Men are captured by the sentient island Krakoa, Xavier assembles a new team to rescue them, including Cyclops' and Havok's long-lost brother, Vulcan,[38] along with Darwin, Petra, and Sway.
When Jean Grey returns from the Savage Land to tell him that all the X-Men are dead, he shuts down the school and travels with Lilandra to her kingdom, where she is crowned Empress and he is treated like a child or a trophy husband.
In a battle with his old foe, the Shadow King, in the "Muir Island Saga", Xavier's spine is shattered, returning him to his former paraplegic state, while his son David is seemingly killed.
[72][73][74][75] Mystique and her Brotherhood start a deadly assault on Muir Isle by releasing an altered form of the Legacy Virus, all in retaliation against the election campaign of Robert Kelly, a seeming mutant-hater.
[75] As Beast cures the Legacy Virus, many infected Genoshan mutants recover overnight, providing Magneto, the current ruler of Genosha, with an army to start the third World War.
Professor X leaves after learning even he can no longer trust the others, yet appears to have severely restricted the number of people he informs of the forthcoming alien invasion, as the X-Men were not prepared for the Skrulls, at least at first.
[103] During the Dark Avengers' arrival in San Francisco to enforce martial law and squelch the anti-mutant riots occurring in the city, Xavier appears (back in his wheelchair) in the company of Norman Osborn and publicly denounces Cyclops' actions and urges him to turn himself in.
[104] The real Xavier is shown in prison on Alcatraz and slowly being stripped of his telepathic powers while in psionic contact with Beast, who was arrested earlier for his part in the anti-mutant riots.
Xavier had wanted to return to the mainland to clear his name, but in the aftermath of Osborn declaring Utopia as a mutant detention area, Cyclops refused to let him leave, stating that it would be a tactical advantage to have him as an ace in the hole in case the need arose.
[121] During a fight with the Stark Sentinels, Doctor Strange and Scarlet Witch attempt to cast a spell to invert the axis of Red Skull's brain and bring out the fragment of Professor X to defeat Onslaught.
[134] Xavier and Magneto reveal the contents of the USB drive to Cyclops, which are shown to be information on Orchis, an organization dedicated to responding to a large-scale mutant threat and the plans of a Mother Mold.
To detect mutants to a wider area beyond this radius, he must amplify his powers through Cerebro and subsequently Cerebra, computer devices of his own design which are sensitive to the psychic/physical energies produced by the mind.
The Professor, using the moniker X, fashioned a Cerebro like a helmet which acts as a focusing device for his psionic powers[133] and used it to galvanize latent aspects of his X-Gene to stimulate some dormant properties, seemingly using telekinesis to will a flash drive on Mystique's person into his hand.
[157] Due to the tampering of Bastion and his Sentinels, the X-Mansion computer system Cerebro gains autonomy and seeks to destroy the X-Men by employing its knowledge of the Xavier Protocols.
When the young man named Werner – born with angel's wings – was to be burnt at the stake by the Inquisition, Javier sent his team leader, Scotius Summerisle, and Roberto Trefusis to rescue the boy.
[volume & issue needed] Nicholas Fury, the Queen of England's spymaster, came to visit Javier at his school and warn him of the danger posed by Elizabeth's death and the eventual rise to power of King James of Scotland, who had no love for witchbreed.
Strange told them that the world was coming to an end and the only way to save it would be to launch an attack on the castle of Otto von Doom, and steal away the treasure of the Templars and the survivors from the Four of the Fantastick.
[volume & issue needed] The band of heroes set sail for the New World to fix the tear in time that had created the weather anomalies circling the globe, as well as endangering the universe itself.
[volume & issue needed] Before parting, Enrique explained his terms: that he would head north, and no one would follow him or investigate him; and that Javier would teach his children, Wanda and Petros, but not reveal to them that he was their father, though he would return one day to fetch them.
[volume & issue needed] When the Scarlet Witch altered reality so Magneto ruled over the Earth and mutants were the dominant species, Professor X is initially depicted as missing; Wolverine attempts to locate him but his search turns up fruitless.
In the Marvel Zombies/Army of Darkness crossover, a zombified Beast informs Doctor Doom of Xavier's death, and that it was the Zombie Reed Richards who reprogrammed Cerebro to seek out humans.
[volume & issue needed] In the Ultimate Marvel continuity, Professor Charles Xavier is the world's most powerful telepath, the founder and patron of the X-Men and a world-famous lecturer for pacifism and mutant emancipation.
It is unconfirmed if this is truly Xavier, as both William Stryker, Alex Summers and Quicksilver have been seen talking to their supposedly dead loved ones, hinting at a foe mentally manipulating several characters.