[1] Progress M-46 was launched by a Soyuz-U carrier rocket from Site 1/5 at the Baikonur Cosmodrome.

[1] The spacecraft docked with the aft port of the Zvezda module at 05:36:30 UTC on 29 June 2002.

[3] It remained docked for 87 days before undocking at 13:58:49 UTC on 24 September 2002[2] to make way for Progress M1-9.

[2] The spacecraft burned up in the atmosphere over the Pacific Ocean, with any remaining debris landing in the ocean at around 10:21:59 UTC.

[2][5] Progress M-46 carried supplies to the International Space Station, including food, water and oxygen for the crew and equipment for conducting scientific research.