This was the last flight of Endeavour before entering its Orbiter Major Modification period until STS-118 in 2007, which included modernizing the cockpit, and also the final shuttle mission before the Columbia disaster.

Mission Specialists John Herrington and Michael López-Alegría performed three spacewalks to activate and outfit the P1.

Also carried aboard STS-113 was the Micro-Electromechanical System (MEMS) based Pico Satellite Inspector (MEPSI).

Because Endeavour entered its Orbiter Major Modification period after the Columbia disaster, this was the last shuttle mission to fly with an analog-style cockpit.

This article incorporates public domain material from websites or documents of the National Aeronautics and Space Administration.